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Dosing

WAKIX Offers Convenient Once-Daily Dosing

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Recommended dosage range for WAKIX: 17.8 mg to 35.6 mg taken once daily in the morning upon wakening

  • WAKIX is available in two tablet strengths for titration and flexible dosing: 4.45 mg and 17.8 mg
    WAKIX is initiated at 8.9 mg once daily in Week 1, increased to 17.8 mg once daily in Week 2, and may be increased to the maximum potential dosage of 35.6 mg once daily in Week 3WAKIX is initiated at 8.9 mg once daily in Week 1, increased to 17.8 mg once daily in Week 2, and may be increased to the maximum potential dosage of 35.6 mg once daily in Week 3
  • After initiating treatment with WAKIX, it is important to regularly assess patients for symptom improvement and tolerability Dose may be adjusted based on tolerability

Dosage modifications are recommended for patients:

  • With moderate hepatic impairment
  • With moderate or severe renal impairment
  • Known to be poor CYP2D6 metabolizers
  • Receiving concomitant strong CYP2D6 inhibitors or strong CYP3A4 inducers

See Full Prescribing Information for recommended dosage and titration.

Dosing WAKIX with other medications tool

Dosing WAKIX with other medications

Some medications have clinically important drug interactions with
WAKIX. Identify drug interactions and recommendations for dosing
WAKIX with other medications.

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