Dosing
Dosing in Adult Patients
Dosing in Pediatric Patients
(6 Years and Older)
(6 Years and Older)
Recommended dosage range for WAKIX for the treatment of EDS or cataplexy in adult patients: 17.8 mg to 35.6 mg taken once daily in the morning upon wakening
- WAKIX is available in two tablet strengths for titration and flexible dosing: 4.45 mg and 17.8 mg
- After initiating treatment with WAKIX, it is important to regularly assess patients for symptom improvement and tolerability
- Dose may be adjusted based on tolerability
Dosage modifications are recommended for patients:
- With moderate hepatic impairment
- With moderate or severe renal impairment
- Receiving concomitant strong CYP2D6 inhibitors or strong CYP3A4 inducers
- Known to be poor CYP2D6 metabolizers
See Full Prescribing Information for recommended dosage and titration.
Dosing WAKIX with other medications
Some medications have clinically important drug interactions with WAKIX. Identify drug interactions and recommendations for dosing WAKIX with other medications.