Dosing

WAKIX Offers Convenient Once-Daily Morning Dosing

  • WAKIX is available in two tablet strengths for titration and flexible dosing: 4.45 mg and 17.8 mg
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Recommended dosage range for WAKIX for the treatment of EDS or cataplexy in adult patients: 17.8 mg to 35.6 mg taken once daily in the morning upon wakening

Image displaying the recommended titration schedule for WAKIX in adult patients with narcolepsyImage displaying the recommended titration schedule for WAKIX in adult patients with narcolepsy
*Recommended titration schedule. Not all patients respond equally to WAKIX.
  • Dose may be adjusted based on tolerability
  • It may take up to 8 weeks for some patients to achieve a clinical response
  • After initiating treatment with WAKIX, it is important to regularly assess patients for symptom improvement and tolerability
  • If a dose is missed, patients should take the next dose the following day in the morning upon wakening

Dosage modifications are recommended for patients:

  • With moderate hepatic impairment
  • With moderate or severe renal impairment
  • Receiving concomitant strong CYP2D6 inhibitors or strong CYP3A4 inducers
  • Known to be poor CYP2D6 metabolizers

See Full Prescribing Information for recommended dosage and titration.

Watch a video about dosing WAKIX in adult patients

Video thumbnail showing healthcare provider explaining WAKIX dosing to an adult patient with narcolepsy
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Dosing WAKIX with other medications

Some medications have clinically important drug interactions with WAKIX. Identify drug interactions and recommendations for dosing WAKIX with other medications.

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